Crystal structure of human pyruvate dehydrogenase kinase 4 in complex with compound 1
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Crystal structure of human pyruvate dehydrogenase kinase 4 in complex with compound 1 Descriptor: 1,3-dihydro-2H-indol-2-one, SULFATE ION, [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, ... Authors: Orita, T, Doi, S, Iwanaga, T, Adachi, T. Deposit date: 2021-03-08 Release date: 2021-08-04 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Fragment-based lead discovery to identify novel inhibitors that target the ATP binding site of pyruvate dehydrogenase kinases. Bioorg.Med.Chem., 44, 2021
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2021-03-08
