Serial (SSX): Southampton, Essex, Exeter, KCL, UCL, Leicester, St Andrews Block Allocation Group (BAG)

The BAG coordinates work in serial synchrotron crystallography, SSX. We propose to collect low dose ground states on enzymes, ligand complexes, and redox sensitive metallo-proteins, using the fixed target chip or foil sample delivery systems at ID29. For time resolved work, we propose laser activated work as well as mixing experiments using tape-drive delivery. Further, we are interested in developing our microfluidic setup together with the ID29 team for fast mixing applications in time resolved work, which will require modifying the sample environment. This bag is further extending as we are additionally joined by two groups from Imperial College London and St Andrews University. We require access to icOS and TricOS to probe for reaction intermediates, to BM07 online spectroscopy, to standard crystallography beamlines to refine crystallisation and substrate addition and potentially request a humidifier at the beamline as well as anaerobic capability.