Crystal structure of wild type HIV-1 protease with macrocyclic inhibitor GRL-0216A
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Crystal structure of wild type HIV-1 protease with macrocyclic inhibitor GRL-0216A Descriptor: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(1S,2R)-1-benzyl-2-hydroxy-3-[(7E)-13-methoxy-1,1-dioxido-3,4,5,6,9,10-hexahydro-2H-11,1,2-benzoxathiazacyclotridecin-2-yl]propyl}carbamate, GLYCEROL, IODIDE ION, ... Authors: Chumanevich, A.A, Wang, Y.-F, Kovalevsky, A.Y, Weber, I.T. Deposit date: 2009-07-07 Release date: 2009-09-29 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.17 Å) Cite: Design, Synthesis, Protein-Ligand X-ray Structure, and Biological Evaluation of a Series of Novel Macrocyclic Human Immunodeficiency Virus-1 Protease Inhibitors to Combat Drug Resistance. J.Med.Chem., 52, 2009
创建时间：
2009-07-07
