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New Three-Component Reaction: Novel Formation of a Seven-Membered Ring by the Unexpected Reaction at the γ-Position of the β-Keto Ester

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NIAID Data Ecosystem2026-03-06 收录
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https://figshare.com/articles/dataset/New_Three_Component_Reaction_Novel_Formation_of_a_Seven_Membered_Ring_by_the_Unexpected_Reaction_at_the_Position_of_the_Keto_Ester/3011113
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The novel three-component reaction of aromatic aldehydes, ethylenediamine, and β-keto esters is described. In this reaction, β-keto esters react at the γ-position which is generally unreactive to produce the seven-membered ring compounds. Products have secondary amines and β-enamino esters, which can serve in further functionalizations to produce molecular diversity.
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2007-04-26
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