We profiled gene expression and splicing changes in HCC1806 human TNBC cells overexpressing three splicing factor genes (SRSF2-SRSF3-SRSF7), all three splicing factors (called 3xSR) or MYC. We perfo
AbstractTriple-negative breast cancer (TNBC) remains one of the most lethal breast cancer subtypes dueto its high metastatic potential and lack of targeted therapies. While oncogenic drivers of metast
Id1 and its closely related family member Id3 are expressed by a diversity of stem and progenitor cells. We show that Id1/3 are required for the self-renewal and proliferation of triple negative breas