Transcriptional response of the Anopheles coluzzii midgut to its microbiota over the blood feeding cycle

Manipulation of the mosquito gut microbiota can lay the foundations for novel methods for disease transmission control. Mosquito blood feeding triggers a significant transient increase of the gut microbiota, but little is known about how the gut epithelium responds to this. In this study we profile the gut epithelial transcriptional response to the changing microbiota load upon blood feeding in the malaria vector Anopheles coluzzii.