The prediction of peptide binders to Major Histocompatibility Complex (MHC) class II receptors is of great interest to study autoimmune diseases and for vaccine development. Most approaches predict th

NIAID Data Ecosystem40

GENE V PROTEIN MUTANT WITH VAL 35 REPLACED BY ILE 35 AND ILE 47 REPLACED BY VAL 47 (V35I, I47V)

蛋白质晶体

点突变效应分析

GENE V PROTEIN MUTANT WITH VAL 35 REPLACED BY ILE 35 AND ILE 47 REPLACED BY VAL 47 (V35I, I47V) Descriptor: GENE V PROTEIN Authors: Zhang, H, Skinner, M.M, Sandberg, W.S, Wang, A.H.-J, Terwilliger, T.

Protein Data Bank Japan2024-02-14 更新20

Probing the regulatory effects of specific mutations in three major binding domains of the pleiotropic regulator CcpA of Bacillus subtilis

细菌转录调控

点突变效应分析

Study the effect of single amino acid point mutations in CcpA at the transcriptome level. Cells were grown in LB with or without 1% glucose and harvested at an OD600 of 0.3 (early exponential phase).

NIAID Data Ecosystem40

DeepDDG: Predicting the Stability Change of Protein Point Mutations Using Neural Networks

蛋白质稳定性

点突变效应分析

Accurately predicting changes in protein stability due to mutations is important for protein engineering and for understanding the functional consequences of missense mutations in proteins. We have de

NIAID Data Ecosystem30

ClpC1 wild-type and mutant protein sequence (FASTA format)

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