Differentiation of naive CD4+ T cells into effector T cells is a dynamic process in which the cells are polarized into T helper (Th) subsets. The subsets largely consist of four fundamental categories
The purpose of this experiment is to follow the differentiation of naive CD8 T cells in memory CD8 T cells in response to virus infection or tumor growth. To do so, naive C57Bl/6J mice were transferre
In addition to serum immunoglobulins, memory B cell (MBC) generation against SARS-CoV-2 represents another layer of immune protection. We studied longitudinal cohorts of naive individuals and disease-
We assessed the global transcriptional changes driven by STING activation with the cyclic dinucleotide 2'3'-cGAMP TH1 and TH9 cells polarized in vitro for 16h and 48h. Our data indicated that STING ac