Human BACE-1 complex with NB-216
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Human BACE-1 complex with NB-216 Descriptor: (4S)-4-[(1R)-1-hydroxy-2-({1-[3-(1-methylethyl)phenyl]cyclopropyl}amino)ethyl]-19-(methoxymethyl)-11-oxa-3,16-diazatric yclo[15.3.1.1~6,10~]docosa-1(21),6(22),7,9,17,19-hexaen-2-one, Beta-secretase 1 Authors: Rondeau, J.-M. Deposit date: 2009-10-07 Release date: 2010-03-02 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.12 Å) Cite: Macrocyclic BACE-1 inhibitors acutely reduce Abeta in brain after po application. Bioorg.Med.Chem.Lett., 20, 2010
创建时间：
2009-10-07
