Supplementary Figure 4. gH mAbs are specific for HCMV neutralization. Neutralization of HSV-1 US-11 GFP (MOI 0.01) using anti-gH mAbs (50-0.016 ug/mL) and assessed usingGFP as a readout for infection
Comparison of neutralization potencies of VHH and mAb b12 in TZM-b1 neutralisation assay against 26 viruses. IC50 values above 50 µg/mL are marked as • and IC50 values of A12, C8 and mAb b12 are cited
1days post onset of symptoms. 2Last positive titer in 90% Focus-reduction micro-neutralization (FRμNT) assay. 3Calculated actual 90% neutralization titers based on a nonlinear regression of the FRμNT
