PhD_Thesis_Supplementary_Tables_Dragomir_Damnjanovic

Host-parasite relationships are defined by a wide spectrum of biotic and abiotic factors. Genetic adaptations and limitations of both host and parasite species in accordance with environmental resources and stress characterize the nature of these interactions on an evolutionary time scale. With the usage of several genetically and ecologically distinct avian host systems: Eurasian bluethroat (Luscinia svecica), Little spiderhunter (Arachnothera longirostra), White-rumped shama (Copsychus malabaricus) and Blue-winded pitta (Pitta moluccemsis) occupying two distinct biogeographical realms, we described prevalence and diversity of malaria causing parasites and their relationship with the triplet of immunity genes in birds. By assessing genomic and genetic profiles of host and parasite species through the double digest restriction-site associated DNA (ddRADseq, in case of the bluethroats), mtDNA diversity (all birds) and amplicon sequencing (immunogenetic for birds and mtDNA for parasites) we revealed their contemporary diversity and population structure, as well as demographic histories and species phylogenies. Our results revealed that the explanatory genetic information uncovers proportions of shared and specific patterns of host-parasite assemblages across ecological and geographical scales.

宿主-寄生虫关系由广泛的生物和非生物因素所界定。在进化时间尺度上，宿主和寄生虫物种根据环境资源和压力的遗传适应与局限性，共同塑造了这些相互作用的本质。通过运用多种在遗传和生态上具有显著差异的鸟类宿主系统，包括欧亚蓝喉鸲（Luscinia svecica）、小蜘蛛鸟（Arachnothera longirostra）、白腰噪鹛（Copsychus malabaricus）和蓝风鸟（Pitta moluccemsis），这些鸟类占据了两个不同的生物地理区域，我们描述了疟原虫的流行率和多样性及其与鸟类免疫基因三联体的关系。通过评估宿主和寄生虫物种的基因组与遗传特征，包括蓝喉鸲的双消化限制性片段长度多态性（ddRADseq）、所有鸟类的线粒体DNA多样性以及扩增子测序（鸟类免疫遗传学和寄生虫的线粒体DNA），我们揭示了它们的当代多样性和种群结构，以及种群历史和物种系统发育。我们的研究结果揭示了解释性遗传信息揭示了宿主-寄生虫组合在生态和地理尺度上共享和特定模式的比率。