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Copper(I)-Catalyzed Intramolecular Trifluoromethylation of Methylenecyclopropanes

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Figshare2016-02-12 更新2026-04-29 收录
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Copper­(I)-catalyzed intramolecular trifluoromethylation of methylene­cyclopropanes has been developed to produce a variety of CF3-substituted dihydro­naphthalenes in moderate to good yields, relying on the construction of C­(sp2)–CF3 bonds under mild conditions. The reactions proceed through a radical process under copper­(I) catalysis with a good compatibility for the functional group.

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2016-02-12
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