Diet-induced obesity Kozak1_ABI_ING

The experimental goals of this study were to determine differences in adipose tissue gene expression in genetically identical mice that have variability in their susceptibility towards diet-induced obesity following 4 weeks feeding a high saturated fat diet. Keywords: comparative gene expression analysis Gene expression analyses was performed from pooled inguinal fat RNA from male C57BL/6J mice exhibiting high or low weight gain after 4 weeks on a high saturated fat diet (D12331; Research Diets, New Brunswick, NJ). Mice were singly-housed at weaning and fed the high saturated diet starting at 8 weeks fo age. Three technical replicates were performed for each pool of RNA from high (H1, H2 and H3) and low (L1, L2 and L3) weight gaining mice.