Structure of the binding domain of BoNT/A mutant H1253K in complex with the GM1a ganglioside receptor
收藏Protein Data Bank Japan2025-08-27 更新2026-04-19 收录
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Structure of the binding domain of BoNT/A mutant H1253K in complex with the GM1a ganglioside receptor Descriptor: Botulinum neurotoxin A heavy chain, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose Authors: Masuyer, G, Stenmark, P. Deposit date: 2024-02-01 Release date: 2025-02-12 Last modified: 2025-08-27 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Botulinum neurotoxin A mutants with enhanced ganglioside binding show improved potency and altered ganglioside selectivity. Commun Chem, 8, 2025
创建时间:
2024-02-01



