five

PXR in complex with P2X4 inhibitor compound 25

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Protein Data Bank Japan2024-01-24 更新2026-03-21 收录
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PXR in complex with P2X4 inhibitor compound 25 Descriptor: (2~{R})-~{N}-[4-(3-chloranylphenoxy)-3-sulfamoyl-phenyl]-2-phenyl-propanamide, DIMETHYL SULFOXIDE, GLYCEROL, ... Authors: Hillig, R.C, Puetter, V, Werner, S, Mesch, S, Laux-Biehlmann, A, Braeuer, N, Dahloef, H, Klint, J, ter Laak, A, Pook, E, Neagoe, I, Nubbemeyer, R, Schulz, S. Deposit date: 2018-10-05 Release date: 2019-12-04 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.22 Å) Cite: Discovery and Characterization of the Potent and Selective P2X4 InhibitorN-[4-(3-Chlorophenoxy)-3-sulfamoylphenyl]-2-phenylacetamide (BAY-1797) and Structure-Guided Amelioration of Its CYP3A4 Induction Profile. J.Med.Chem., 62, 2019
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2018-10-05
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