Antioxidant parameters and cognitive function according to FV consumption and individual GST genotype.

General linear model used. Data are presented as the mean ± SE. For antioxidant biomarker data analysis, factors including age, sex, BMI, smoking and antioxidant supplement were adjusted. For cognitive function (MoCA score) data analysis, factors including age, sex, BMI, education, family history of AD, physical activity and participation in cognitive activity were adjusted. FV, fruit and vegetable; GSH-Px, glutathione peroxidase; GST, glutathione S-transferase; GR, glutathion reductase; CAT, catalase; SOD, superoxide dismutase; GSH, glutathione; T-AOC, total antioxidant capacity; MoCA, Montreal Cognitive Assessment. P valuea: GSTM1 genotype affect the erythrocyte GST enzyme activity, PGSTM1 genotype = 0.012, b: FV consumption affect the plasma T-AOC in the subjects with different GSTT1 genotypes, PFV = 0.04, c: Interaction of FV and GSTT1 genotype on cognitive function was detected, PFV and GSTT1 genotype interaction = 0.033, Antioxidant parameters and cognitive function according to FV consumption and individual GST genotype.