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Assessment of In Vivo Chemical Mutagenesis by Long-Read Sequencing

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1138729
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资源简介:
In this study, we evaluated whether long-read PacBio-based HiFi sequencing (HiFi seq), which has integrated error-correction, can detect de novo mutations induced by mutagens in C57BL/6 mouse tissues. The mutagens used were 7,12-dimethylbenz[a]anthracene (DMBA), procarbazine (PCZ), and N-propyl-N-nitrosourea (PNU), and the tissues sampled were kidney, liver, lung, and spleen.
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2024-07-22
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