Comparison of humanized PRMT1 to the mouse wild-type
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/DRP013553
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资源简介：
PRMT1 is a key enzyme responsible for protein arginine methylation. Only a single amino acid substitution at position 179 exists between mice (histidine) and humans (tyrosine). Here, we have generated a humanized PRMT1 mouse model (huMice) in which the amino acid sequence of mouse PRMT1 is replaced with the human form. We performed bulk RNA-seq using huMice and wild-type (WT) mouse embryonic fibroblasts to reveal the biological differences.
创建时间：
2025-07-06
