Three-Component Coupling Reaction Triggered by Insertion of Arynes into the SO Bond of DMSO

An unprecedented three-component coupling reaction of arynes, α-bromo carbonyl compounds, and DMSO triggered by insertion of arynes into the SO bond of DMSO has been developed. The reaction can generate a wide range of multi­substituted aryl methyl thioethers in good yields, wherein DMSO serves as both methyl­thiolation reagent and oxygen source.