HSP90 MIND-S Model
收藏Mendeley Data2025-01-01 更新2026-04-09 收录
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https://data.mendeley.com/datasets/dk8yb2prrw/1
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资源简介：
HSP90 is at the hub of proteostasis and cellular signaling networks in cancer. Post-translational modification (PTM) of proteins regulates cellular proteostasis by expanding protein functional diversity. This dataset contains the original code for a deep-learning artificial intelligence (AI) prediction model created to decipher PTM crosstalk on HSP90. Fine-tuning of the model was achieved using experimental mass-spectrometry data of wild type (WT) alpha and beta isoforms of HSP90, as well as variants carrying two specific mutations, lysine-to-glutamine (K→Q) and lysine-to-arginine (K→R) to capture potential PTM patterns across isoforms and mutation contexts.
创建时间：
2025-01-01
