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资源简介：
Alzheimer's disease and perivascular macrophages
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创建时间：
2025-05-08
相关数据集
Novel Alzheimer risk genes determine the microglia response to amyloid-β but not to TAU pathology. Novel Alzheimer risk genes determine the microglia response to amyloid-β but not to TAU pathology
Polygenic risk scores have identified that genetic variants without genome-wide significance still add to the genetic risk of developing Alzheimer’s disease (AD). Whether and how subthreshold risk loc
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Table_6_Network pharmacology analysis reveals neuroprotective effects of the Qin-Zhi-Zhu-Dan Formula in Alzheimer’s disease.xlsx
There is yet no effective drug for Alzheimer’s disease (AD) which is one of the world’s most common neurodegenerative diseases. The Qin-Zhi-Zhu-Dan Formula (QZZD) is derived from a widely used Chinese
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Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer’s disease model. Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer’s disease model
This dataset allows for the exploration of microglial function on gene expression in wild-type and the 5xFAD mouse model of Alzheimer's disease, across multiple brain regions. Mice were treated with t
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AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation
The hemizygous R47H variant of TREM2, a microglia-specific gene in the brain, increases risk for late-onset Alzheimer's disease (AD). Using transcriptomic analysis at the single-nuclei level from brai
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