Expression data from regenerating prostates of wild-type or Gli1-/- mutant mice. Mus musculus

Attenuation of Hedgehog (Hh) pathway activity leads to increased prostate branching during adult prostate regeneration. In order to identify genes regulated by the Hh pathway that might be involved in adult prostate branching, we performed transcriptional profiling of regenerating prostates from wild-type or Gli1-/- mutant mice, which have attenuated Hh pathway activity. Overall design: 6 total samples were analyzed. 3 wild-type prostates and 3 Gli-/- mutant prostates were analyzed.