Single cell profiling shows that murine forebrain neural stem cells reacquire a developing precursor state when activated to make adult-born neurons
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=feb6d0b62de684b67ee152db10e2d760
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资源简介：
In this study, we have utilized a single-cell RNA-Sequencing platform coupled with transgenic lineage tracing in order to follow the progression of different embryonic neural stem cell populations as they progress into adult dormant neural stem cells. We show that adult dormant V-SVZ neural stem cells of different embryonic origins share a common molecular signature and reacquire an embryonic precursor-like state when activated to make new neurons in the adult brain.
提供机构：
Hospital for Sick Children
创建时间：
2022-02-20
