The data of study about the chitosan-selenium nanoparticles on depression-like behaviour induced by fluoride in mice via JAK2-STAT3 pathway

These data showed the morphology, product composition and crystal structure of CS-SeNPs. Data1 found that the distribution frequency of CS-SeNPs with a particle size of 41.5-48.8 nm was the highest, namely 19.48%. Data 1 also demonstrated that the diameter of manufactured CS-SeNPs was all less than 100 nm, in line with the preparation requirements of nanomaterials. Data 2 showed the maximum absorption of the CS-SeNPs system was at 245 nm, and there was absorption in the visible region of 300~600 nm, which indicated that the prepared CS-SeNPs are different from the simple mixing of solution, that is, the new substance CS-SeNPs is generated. Moreover, Data 3 of Raman spectrum analysis showed one resonance peak of CS-SeNPs was identified at 246 cm−1 depicted monoclinic Se (m-Se). However, there is no signal absorption peak around 234cm-1, or the signal of absorption peak is very weak, indicating that there is no trigonal Se (t-Se) or the amount of it is very small. In addition, Data 4 and 5 claimed that CS-SeNPs were able to clear •DPPH and •ABTS in a dose-dependent manner, and their capacity to scavenging radicals was stronger than that of Vc, which was equal to approximately 8 times (•DPPH) or 20 times (•ABTS) of that of Vc, was acceptable.
These data could be used for the These data can be used to understand the physical and chemical and biological characteristics of the materials prepared in this study of CS-SeNPs. It can also be compared with nanomaterials prepared by other methods. Furthermore, it was revealed that it had excellent antioxidant activity to provide data support.