Dysfunction and stemness of tumor-infiltrating T cells are triggered by a common mechanism
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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The paradox of tumor immunology is that tumor infiltrating lymphocytes (TILs) are dysfunctional in situ and yet are capable of stem cell-like behavior with self-renewal, massive expansion, multipotency, and eradication of large metastatic tumors. Here we report that the overabundance of potassium in the tumor microenvironment (TME) can explain both phenomena.
提供机构：
NCI
创建时间：
2022-02-20
