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Potent macrocyclic renin inhibitors

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Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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Potent macrocyclic renin inhibitors Descriptor: (2S,4S)-4-hydroxy-2-(1-methylethyl)-4-[(4R,13S)-18-[methyl(methylsulfonyl)amino]-2,15-dioxo-4-phenyl-11-oxa-3,14-diazatricyclo[14.3.1.1~5,9~]henicosa-1(20),5(21),6,8,16,18-hexaen-13-yl]-N-(2-methylpropyl)butanamide, (2S,4S)-4-hydroxy-2-(1-methylethyl)-4-[(4S,13S)-18-[methyl(methylsulfonyl)amino]-2,15-dioxo-4-phenyl-11-oxa-3,14-diazatricyclo[14.3.1.1~5,9~]henicosa-1(20),5(21),6,8,16,18-hexaen-13-yl]-N-(2-methylpropyl)butanamide, ACETATE ION, ... Authors: Borkakoti, N, Derbyshire, D. Deposit date: 2010-09-20 Release date: 2010-12-15 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Design and synthesis of potent macrocyclic renin inhibitors. Bioorg.Med.Chem.Lett., 21, 2011
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2010-09-20
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