Single-cell transcriptome analysis reveals abnormal angiogenesis and placentation by loss of imprinted glutaminyl-peptide cyclotransferase

We provided a comprehensive transcriptome profile of Qpct-/- and Qpct+/+ mouse placentae and fills the gap of function of maternally expressed gene Qpct in mouse placental development We performed the single-cell and single-nucleus RNA library in Qpct+/+ and Qpct-/- mouse placentae (5 placenta as a pool n=5)