B16-F10 cells were first injected into the right axilla of BALB/c mice to establish the model. When the tumor size reached approximately 100 mm3, the mice were randomly divided into two groups: the An
Twenty-four mice were randomly divided into four groups: control (Ctrl), periodontitis (PD), high-fat diet (HFD), and HFD with periodontitis (HPD). PD and HPD mice developed periodontitis by week 10,