CASB: A concanavalin A-based sample barcoding strategy for single-cell sequencing [mixed Sample of cell lines and organisms]

We reported a Concanavalin A-based Barcoding Strategy (CASB) for single-cell and single-nucleus sample multiplexing, which could be followed by different single-cell sequencing techniques. The method involves minimal sample processing, thereby preserving intact transcriptomic or epigenomic patterns. Besides sample multiplexing, the CASB could further improve data quality through doublet identification. scRNA-seq of MDA-MB-231 cells; snATAC-seq and scRNA-seq of HAP1 cells