Multicenter normative data for mesopic microperimetry

This record contains the analysis and underlying data presented in the manuscript Pfau et al. 'Multicenter normative data for mesopic microperimetry'.

Contents:
2024-08-30_Multicenter-Normal-Data.csv: Newly published normal data for mesopic microperimetry
2024-08-30_Analysis.R: Analysis script
2024-08-30_Vignette-to-create-normal-data.R: Software example to create normative maps

The subfolders Figures and Tables show the analysis results.
The folder Intermediary_Results contains the results of the cross-validation folds to assess model performance.

To run the analysis code in 2024-08-30_Analysis.R, the following data is needed in addition: Astle et al. Data Brief. 2016 Aug 4;9:673-675. doi: 10.1016/j.dib.2016.07.061

The 2024-08-30_Multicenter-Normal-Data.csv file with the data contains the following columns:
source: Describes the clinical site
MachineID: ID of the MAIA device used for data collection
ParticipantID: ID of the participant
EID: ID of the eye
eye: Laterality (either Right or Left)
sex: Sex (f for female, m for male)
age: Age in years
ExamID: ID of the exam
ExamBaselineID: ID of the corresponding baseline exam (-1 indicates that the exam itself is the baseline exam)
GridUsed: Name of the grid
falsepos: Rate of false positive responses to Heijl-Krakau stimulus presentations to the optic nerve head (blind spot)
bcea63_area_deg2: Fixation stability in terms of the bivariate contour ellipse area covering 63% of the fixation points (in square degree)
bcea95_area_deg2: Fixation stability in terms of the bivariate contour ellipse area covering 95% of the fixation points (in square degree)
pointID: ID of the test point
eccentricity: Eccentricity of the test point (in degree)
x_coord: X-coordinate of the test point (in degree), negative values are temporal to the fovea and positive values are nasal to the fovea (in retinal space)
y_coord: Y-coordinate of the test point (in degree), negative values are inferior to the fovea and positive values are superior to the fovea (in retinal space) sensitivity: Sensitivity at the test point (in dB)