Genes with potentially damaging variants for low-grade astrocytoma.

We included genes that had at least one child but no more than two with a potentially damaging variant. Scores provided by VarElect, our ranked version of the VarElect scores, and our overall ranking are shown for each gene. RP11-294C11.1, SPATA31A6, XIRP2, and Y_RNA were also identified in 2 or less children with potentially damaging variants, but were not able to be ranked by VarElect. The number of potentially damaging variants in each gene is one unless specified with n. Abbreviations: het = simple heterozygous. SNP = single nucleotide polymorphism. del = deletion. SV = structural variant. (XLSX)