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Intramolecular Schmidt Reaction of Acyl Chlorides with Alkyl Azides: Rapid Access to Fused Polycyclic Nitrogen-Containing Heterocycles via a Multistep One-Pot Transformation

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NIAID Data Ecosystem2026-03-07 收录
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https://figshare.com/articles/dataset/Intramolecular_Schmidt_Reaction_of_Acyl_Chlorides_with_Alkyl_Azides_Rapid_Access_to_Fused_Polycyclic_Nitrogen_Containing_Heterocycles_via_a_Multistep_One_Pot_Transformation/2468512
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资源简介:
The first intramolecular Schmidt reaction of acyl chlorides with alkyl azides has been developed. In this one-pot conversion, an ω-azido hydrocinnamic acid is converted to a tricyclic lactam. The most important feature of the process is the efficiency in bond formation (one bond broken and three new bonds created) and ring construction (two new rings formed).
创建时间:
2016-02-20
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