JNK-mediated control of gene expression in liver

RNAseq analysis of gene expression in Liver of Control and JNK deficient mice fed a control or a High fat diet Contro(Albcre+)l and mice with liver-specific defiency of JNK (Alb Cre+ Jnk1flox/flox, Jnk2flox/flox or Jnk1flox/floxJnk2flox/flox) were fed a control or a high fat diet for 16 weeks. Gene expression analysis in liver was analyzed by RNAseq本数据集针对喂食对照饲料或高脂饲料的对照小鼠与肝脏特异性JNK缺陷小鼠的肝脏基因表达开展RNA测序（RNAseq）分析。其中，对照小鼠（AlbCre+）以及三类肝脏特异性JNK缺陷小鼠（分别为AlbCre+ Jnk1flox/flox、Jnk2flox/flox及Jnk1flox/floxJnk2flox/flox）均接受为期16周的对应饮食干预，后续通过RNAseq对其肝脏组织的基因表达水平进行了检测分析。