opto-8: tDCS effects during light-evoked firing

Dataset 8 – tDCS effects during light-evoked firing Dataset descriptionExperiment: Modulation of light-evoked spiking activity by anodal and cathodal tDCS ##Dataset descriptionThis dataset corresponds to the evaluation of how transcranial direct current stimulation (tDCS) modulates the firing responses of cortical neurons to light pulses in the mouse primary somatosensory cortex (S1). **Experiment protocol:**- Single photostimulation pulses (10 ms, 20 mA) were delivered in S1 during both control and tDCS conditions.- **tDCS protocol:** - 5 s ramp-up - 5 s steady-state - 5 s ramp-down - 10 s without stimulation- Light pulses were delivered during the **steady-state phase** of tDCS and in the control condition.- tDCS intensities: ±50, ±100, ±150, ±200 μA (randomized).- Subjects: 208 neurons recorded, including: - Group 1: ChR2 expressed in glutamatergic neurons - Group 2: ChR2 expressed in GABAergic neurons The goal was to determine whether tDCS modulates light-evoked firing and whether effects depend on neuronal subtype or tDCS polarity. **Recording parameters (spike data):**- Sampling rate: 30 kHz- High-pass filter: 0.3 Hz- Low-pass filter: 10 kHz --- ## Data organizationData follow a pseudo-BIDS structure: tDCSNeurons-duringLight/├── README.txt # Protocol summary and dataset information├── participants.tsv # Subjects and neuronal classification└── sub-XX/ └── ses-01/ ├── ControlAnodal-Data.mat ├── Anodal50-Data.mat ├── Anodal100-Data.mat ├── Anodal150-Data.mat ├── Anodal200-Data.mat ├── ControlCathodal-Data.mat ├── Cathodal50-Data.mat ├── Cathodal100-Data.mat ├── Cathodal150-Data.mat ├── Cathodal200-Data.mat Access before the embargo ends: the files are under embargo until 30 June 2027. To request access before then, email Ricardo Salvador ([e-mail]) with a short description of the intended use.