Inhibition of CXCR1/2 in human colitis-derived pluripotent stem cell intestinal organoids attenuates the inflammatory phenotype. Inhibition of CXCR1/2 in human colitis-derived pluripotent stem cell intestinal organoids attenuates the inflammatory phenotype

We report the results of RNA-Seq on iPSCs, Definitive Endoderm (DE), Spheroids (Sph), and induced human intestinal organoids (iHIOs) from colitic and normal primary patient colon tissues Overall design: Transcriptome analysis of iPSCs, DE, Spheroids and iHIOs isolated from colitic and normal primary tissues.