BAF complex cooperates with c-Myc to orchestrate early fate decisions of CD8 T cells (RNA-seq)
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https://www.ncbi.nlm.nih.gov/sra/SRP336042
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资源简介：
We found cBAF and c-Myc co-assort asymmetrically to the two daughter nuclei, such that daughter cells with low c-Myc and cBAF display a cell fate trajectory towards memory T cell differentiation. Moreover, cBAF complex and c-Myc physically interact with each other, and act in establishing the chromatin landscape in activated CD8 T cells. Overall design: RNA-seq analysis of 20 samples: Activated CD8 T cells (n=5); Activated c-Myc KO CD8 T cells (n=5); First-division WT CD8 T cells (n=5); First division Arid1a KO CD8 T cells (n=5)
创建时间：
2022-07-09
