Assessment of gut microbiota among patients with irritable bowel syndrome

Irritable bowel syndrome (IBS) is a chronic functional gastrointestinal disease that affects approximately 11% of the general population. The gut microbiota, among other known factors, plays a substantial role in its pathogenesis.The study aimed to characterize the gut microbiota differences between patients with IBS and unaffected individuals, taking into account the gender aspect of the patients, and the types of IBS determined on the basis of the Rome IV Criteria, the IBS-C, IBS-D, IBS-M, and IBS-U. 121 patients with IBS and 70 unaffected individuals participated in the study; the derived stool samples were subjected to 16S amplicon sequencing.