Transcriptome profile of MafB-cKO Sertoli cells.
收藏NIAID Data Ecosystem2026-04-25 收录
下载链接：
https://www.ncbi.nlm.nih.gov/sra/SRP098590
下载链接
链接失效反馈官方服务：
资源简介：
MafB is a transcription factor acts as an important regulator of the development and differentiation of various organs and tissues. MafB is expressed in sertoli, leydig, and germ cells in adult mice testis. However, analysis of MafB cKO mice testis showed no dissruption of spermatogenesis or obvious abnormal structure. Thus, the exact function is unclear. We examined any change in the transcriptome profile of MafB-cKO Sertoli cells. Results of signaling pathway analysis of the downregulated genes was related to immune-function but not spermatogenesis. Overall design: Examination of 2 samples (cKO and Control). Each sample contains RNA mixed from 3 mice. Paired-end RNA sequencing was performed with NextSeq500 sequencer (Illumina).
创建时间：
2020-09-23
