Crystal structure of PDE8A catalytic domain in complex with 17
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Crystal structure of PDE8A catalytic domain in complex with 17 Descriptor: 2-chloro-9-(3-(2,2-difluoroethoxy)-5-isopropoxybenzyl)-9H-purin-6-amine, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A, MAGNESIUM ION, ... Authors: Wu, X.-N, Zhou, Q, Huang, Y.-D, Li, Z, Wu, Y, Luo, H.-B. Deposit date: 2021-10-31 Release date: 2022-11-02 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.79971328057 Å) Cite: Structure-Based Discovery of Orally Efficient PDE8 Inhibitors for the Treatment of Vascular Dementia To Be Published
创建时间：
2021-10-31
