Structure-based design of 4-hydroxy-3,5-substituted piperidines as direct renin inhibitors
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Structure-based design of 4-hydroxy-3,5-substituted piperidines as direct renin inhibitors Descriptor: (3S,4R,5R)-N-cyclopropyl-N'-[(2R)-1-ethoxy-4-methylpentan-2-yl]-4-hydroxy-N-[5-(propan-2-yl)pyridin-2-yl]piperidine-3,5-dicarboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... Authors: Schiering, N, D'Arcy, A, Irie, O, Yokokawa, F. Deposit date: 2014-04-04 Release date: 2014-08-06 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.09 Å) Cite: Structure-based design of substituted piperidines as a new class of highly efficacious oral direct Renin inhibitors. ACS Med Chem Lett, 5, 2014
创建时间：
2014-04-04
