Room-temperature X-ray structure of SARS-CoV-2 main protease drug resistant mutant (E166V) in complex with ensitrelvir (ESV)
收藏Protein Data Bank Japan2024-11-06 更新2026-04-19 收录
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Room-temperature X-ray structure of SARS-CoV-2 main protease drug resistant mutant (E166V) in complex with ensitrelvir (ESV) Descriptor: 3C-like proteinase nsp5, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione Authors: Kovalevsky, A, Coates, L, Gerlits, O. Deposit date: 2024-07-15 Release date: 2024-10-16 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Effects of SARS-CoV-2 Main Protease Mutations at Positions L50, E166, and L167 Rendering Resistance to Covalent and Noncovalent Inhibitors. J.Med.Chem., 67, 2024
创建时间：
2024-07-15
