Gene expression change after JQ1 treatment in breast cancer cell

BET bromodomain inhibitors effectively kill several types of cancer cells. However, the underlying mechanism of BET inhibition resistance remains obscure. We sought to identify the gene expression change upon treatment of JQ1, a well-known BET inhibitor, in basal-like breast cancer cells. In this dataset, we used RNA-sequencing to characterize the mRNA expression profiles from DMSO and JQ1-treated MDA-MB-231 breast tumor cells. Total RNA was extracted from JQ1-treated MDA-MB-231 cells for RNA sequencing. DMSO-treated MDA-MB-231 cells were used as control.