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The djlA Gene Acts Synergistically with dnaJ in Promoting Escherichia coli Growth

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PubMed Central2026-05-16 收录
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The DnaK chaperone of Escherichia coli is known to interact with the J domains of DnaJ, CbpA, and DjlA. By constructing multiple mutants, we found that the djlA gene was essential for bacterial growth above 37°C in the absence of dnaJ. This essentiality depended upon the J domain of DjlA but not upon the normal membrane location of DjlA.

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