Structure of SARS-coV-2 NSP3 macrodomain in complex with ligand

Structure of SARS-coV-2 NSP3 macrodomain in complex with ligand Descriptor: Papain-like protease nsp3, [[(2~{R},3~{S},4~{R},5~{R})-5-(4-azanylpyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] methyl hydrogen phosphate Authors: Ruiz Carrillo, D, Sander, S, Tidow, H, Garcia-Alai, M. Deposit date: 2025-06-09 Release date: 2026-06-24 Last modified: 2026-08-19 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Design, structure-based optimization and antiviral evaluation of potent inhibitors for the macrodomain Mac1 of SARS-CoV-2. Nat Commun, 17, 2026