brandeslab/P-KNN

P-KNN预计算分数数据集提供了通过P-KNN方法使用dbNSFP v5.2（学术版或商业版）进行联合校准生成的致病变异预测分数。该数据集包含了对所有错义突变的致性评估，并根据基因组坐标或MANE Ensembl转录本组织成多个子文件夹。数据集分为学术版和商业版，每个版本都有基于染色体和基因组织的分数。此外，还包括了用于命令行工具的默认校准和正则化数据集，用于研究的额外数据集，以及用于P-KNN预计算分数查看器的重新组织数据。

The P-KNN Precomputed Scores Dataset provides pathogenicity prediction scores precomputed by the P-KNN method using dbNSFP v5.2 (academic or commercial version) with joint calibration. The dataset includes pathogenicity assessments for all missense variants, organized into multiple subfolders based on genomic coordinates or MANE Ensembl transcripts. It is divided into academic and commercial versions, each with scores organized by chromosome and gene. Additionally, it includes default calibration and regularization datasets for the command-line tool, additional datasets used in the study, and re-organized data for the P-KNN precomputed score viewer.