Biochemical correlates of GOLD severity in COPD: serum lipoxin A4, leukotriene B4 and neutrophil activation markers in two independent cohorts

This deposit contains the clinical dataset and reproducibility code supporting a machine-learning study investigating how serum lipid mediators (LXA4, LTB4) and circulating neutrophil-activation markers vary across GOLD spirometric severity strata (stages 1–4) in COPD patients, and whether this panel can stratify disease severity independently of spirometry.