Excel Data S1 - Differentially Expressed Metabolites

The files capture the relationship between viral load and microbial metabolic activity across four main comparison groups: non-detected virus (ND) versus high viral load, ND versus medium viral load, medium versus low viral load, and medium versus high viral load. This comprehensive dataset offers detailed insights into how SARS-CoV-2 infection affects nasopharyngeal microbiome metabolic activities, specifically highlighting viral load-dependent changes in key pathways, such as amino sugar metabolism, fatty acid degradation, and nucleotide sugar biosynthesis. These findings represent a valuable resource for understanding host-microbe interactions during COVID-19 infection and provide insights into the biochemical mechanisms that may contribute to disease pathogenesis.