The small intestine has a robust regenerative capacity, and various cell types serve as âcells-of-originâ in the epithelial regeneration process after injury. However, how much each population con
Background and Aims: Analysis of aging-induced impairments in satellite cells (SCs) â the stem cells of skeletal muscle that are required for its regeneration. Hox genes are known to control stem ce
The stem cell marker Musashi1 (MSI1) is highly expressed during neurogenesis and in Glioblastoma (GBM). In cancer and non-malignant progenitor cells, MSI1 promotes self-renewal and impairs differentia
Tissue homeostasis requires long-term lineage fidelity of somatic stem cells. Whether and how age-related changes in somatic stem cells impact the faithful execution of lineage decisions remains large