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Design and synthesis of hydroxyethylamine (hea) BACE-1 inhibitors: prime side chromane-containing inhibitors

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Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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Design and synthesis of hydroxyethylamine (hea) BACE-1 inhibitors: prime side chromane-containing inhibitors Descriptor: Beta-secretase 1, N-[(2S,3R)-4-{[(2R,4S)-2-cyclopropyl-6-(2,2-dimethylpropyl)-3,4-dihydro-2H-chromen-4-yl]amino}-1-(3,5-difluorophenyl)-3-hydroxybutan-2-yl]acetamide Authors: Yao, N. Deposit date: 2011-01-26 Release date: 2012-03-28 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: prime side chromane-containing inhibitors. Bioorg.Med.Chem.Lett., 23, 2013
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2011-01-26
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