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Genes misregulated in C. elegans deficient in Dicer, RDE-4, or RDE-1 are enriched for innate immunity genes.

Alliance of Genome Resources2026-08-01 收录

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https://www.wormbase.org/resources/analysis/Microarray_Study.WBPaper00029437.ce.mr 数据链接链接失效反馈

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Genes misregulated in C. elegans deficient in Dicer, RDE-4, or RDE-1 are enriched for innate immunity genes.

应用场景：

转录组学分析

RNA干扰通路

To assess the impact of endogenous RNaseIII nucleases on the overall transcriptome and the reseponse to dsRNA. We utilized CRISPR techology to engineer an RNaseIII null cell line using the NoDice 293T

NIAID Data Ecosystem20

Consequences of depleting core RNAi factors on miRNA profiles. Consequences of depleting core RNAi factors on miRNA profiles

miRNA调控

RNA干扰通路

In this study, we used CRISPR/Cas9 to deplete HCT116 cells of DROSHA, AGO1, AGO2, AGO1/2, AGO1/2/3, TNRC6A/B, TNRC6/B + siTNRC6C, TNRC6A/B-/- + siGL2, WT, WT + siGL2, WT + siTNRC6C. Then, we used thes

NIAID Data Ecosystem20

Spatial distribution of three ARGONAUTEs regulates the anther phasiRNA pathway

植物生殖生物学

RNA干扰通路

Image data of Spatial distribution of three ARGONAUTEs regulates the anther phasiRNA pathway

NIAID Data Ecosystem10

Separable roles for RNAi in regulation of transposable elements and viability in the fission yeast Schizosaccharomyces japonicus [RNA-Seq]

RNA干扰通路

转座子转录调控

RNA-seq was performed to identify transcripts differentially expressed in Schizosaccharomyces japonicus cells lacking Dcr1. Overall design: Three biological replicates of RNA profiles in WT and dcr1D

NIAID Data Ecosystem20

Additional file 1 of A genome-wide screening for RNAi pathway proteins in Acari

RNA干扰通路

蜱虫基因组

Additional file 1. Orthologs of RNAi pathway proteins identified in the genome assembly of Metaseiulus occidentalis (Mo) by Proteinortho5 and/or Blastp against NCBI protein database (GCF_000255335.1).

NIAID Data Ecosystem20

Genes misregulated in C. elegans deficient in Dicer, RDE-4, or RDE-1 are enriched for innate immunity genes.

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